Cannabis/cannabinoids intoxication

Cannabis/cannabinoids intoxication occurs when someone uses too much cannabis or related substances, affecting the brain and nervous system. It mainly impacts how a person thinks, feels, and moves, causing symptoms like altered perception, impaired coordination, and changes in mood. The intoxication can lead to difficulty concentrating, slowed reaction times, and sometimes feelings of anxiety or paranoia. These effects result from the active chemicals in cannabis interacting with the body's natural cannabinoid receptors. The condition can affect daily activities and increase the risk of accidents due to impaired judgment and motor skills.

Cannabis/cannabinoids intoxication is a clinical syndrome caused by recent use of cannabis or synthetic cannabinoids leading to acute central nervous system effects. The primary mechanism involves activation of cannabinoid receptors (CB1 and CB2) in the brain, altering neurotransmitter release and neural signaling. Common manifestations include euphoria, impaired motor coordination, altered time perception, anxiety, and cognitive impairment. Physical signs may include conjunctival injection, dry mouth, and tachycardia. The intoxication is usually self-limited but can cause significant functional impairment and risk of injury. It is important to distinguish this from other causes of altered mental status and intoxication.