Retinal Vein Occlusion

Overview


Plain-Language Overview

Retinal Vein Occlusion is a condition that affects the blood vessels in the eye, specifically the veins that drain blood from the retina. The retina is the light-sensitive layer at the back of the eye responsible for vision. When a vein becomes blocked, it causes blood and fluid to leak into the retina, leading to swelling and damage. This can result in sudden, painless vision loss or blurry vision in one eye. The condition mainly affects older adults and those with risk factors like high blood pressure, diabetes, or glaucoma. Early detection is important to prevent permanent vision impairment.

Clinical Definition

Retinal Vein Occlusion (RVO) is a vascular disorder characterized by the obstruction of retinal venous outflow, typically caused by thrombus formation at arteriovenous crossings or within the central retinal vein. The blockage leads to increased venous pressure, retinal hemorrhages, and macular edema, which impair retinal function. RVO is classified into central retinal vein occlusion (CRVO) and branch retinal vein occlusion (BRVO) depending on the site of occlusion. Major risk factors include hypertension, atherosclerosis, diabetes mellitus, and glaucoma. Clinically, RVO presents with sudden, painless vision loss or visual field defects. Complications include neovascularization and secondary glaucoma, which can cause further vision deterioration.

Clinical Presentation


Diagnostic Workup


Pathophysiology


Treatments


Prevention


Outcome & Complications


Differential Diagnoses


Medical Disclaimer: The content on this site is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. If you think you may be experiencing a medical emergency, call 911 or your local emergency number immediately. Always consult a licensed healthcare professional with questions about a medical condition.

Artificial Intelligence Use: Portions of this site’s content were generated or assisted by AI and reviewed by Erik Romano, MD; however, errors or omissions may occur.

Analytics Disclosure: If you allow analytics cookies, Doctogenic uses Google Analytics, Microsoft Application Insights, and Microsoft Clarity to understand site usage, diagnose issues, review heatmaps and session replay recordings, and improve the service on pages where those tools are enabled. Clarity is not enabled on account, purchase, billing, checkout, Stripe-related, or admin pages. You can change this choice through Cookie preferences.

USMLE® is a registered trademark of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). Doctogenic and Roscoe & Romano are not affiliated with, sponsored by, or endorsed by the USMLE, FSMB, or NBME. Neither FSMB nor NBME has reviewed or approved this content. "USMLE Step 1" and "USMLE Step 2 CK" are used only to identify the relevant examinations.