Uterus Didelphys

Overview


Plain-Language Overview

Uterus Didelphys is a rare condition where a woman has two separate uteruses instead of one. This happens because the two tubes that normally fuse to form a single uterus during fetal development do not join properly. It affects the female reproductive system and can sometimes cause problems with menstruation, pregnancy, or fertility. Many women with this condition may not have symptoms and only discover it during an exam for other reasons. However, some may experience painful periods, recurrent miscarriages, or difficulties carrying a pregnancy to term. Diagnosis often involves imaging tests to visualize the uterus. Understanding this condition helps explain certain reproductive challenges.

Clinical Definition

Uterus Didelphys is a congenital malformation characterized by complete failure of fusion of the paired Müllerian ducts during embryogenesis, resulting in two distinct uterine bodies each with its own endometrial cavity and often two cervices. This anomaly is classified as a type III Müllerian duct anomaly and is caused by disrupted embryologic development between weeks 6 and 12 of gestation. It is significant because it can lead to obstetric complications such as recurrent pregnancy loss, preterm labor, and malpresentation. Patients may also present with dysmenorrhea or dyspareunia due to obstructed hemivagina if associated with vaginal septum. Diagnosis is important for appropriate management of reproductive health and pregnancy outcomes.

Clinical Presentation


Diagnostic Workup


Pathophysiology


Treatments


Prevention


Outcome & Complications


Differential Diagnoses


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