Polyposis Syndromes
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Polyposis Syndromes conditions
Familial Adenomatous Polyposis (FAP)Familial Adenomatous Polyposis (FAP) is an inherited disorder causing hundreds of colorectal adenomatous polyps and a high risk of colorectal cancer.Gardner SyndromeGardner Syndrome is a genetic disorder causing multiple colorectal polyps, osteomas, and soft tissue tumors due to mutations in the APC gene.Juvenile Polyposis SyndromeA hereditary disorder causing multiple juvenile polyps in the GI tract, increasing colorectal cancer risk through mutations in SMAD4 or BMPR1A genes.MUTYH-associated Polyposis SyndromeMUTYH-associated Polyposis Syndrome is an inherited disorder causing multiple colorectal adenomas due to MUTYH gene mutations, increasing colorectal cancer risk.Peutz-Jeghers SyndromePeutz-Jeghers Syndrome is a genetic disorder causing mucocutaneous pigmentation and multiple hamartomatous polyps in the gastrointestinal tract, increasing cancer risk.Turcot SyndromeTurcot Syndrome is a rare genetic disorder combining colorectal polyposis with brain tumors, often glioblastomas or medulloblastomas, linked to DNA mismatch repair defects.