Hemoglobinopathies and Thalassemias
Preview this topic section
Each condition includes a free overview and clinical definition. Plans unlock the full Step 1 details.
Hemoglobinopathies and Thalassemias conditions
Alpha-ThalassemiaAlpha-Thalassemia is a genetic blood disorder caused by reduced or absent alpha-globin chain production, leading to anemia and abnormal hemoglobin formation.Beta-ThalassemiaBeta-Thalassemia is a genetic blood disorder causing reduced beta-globin chain production, leading to anemia, ineffective erythropoiesis, and microcytic hypochromic red cells.HbC DiseaseHbC disease is a hemoglobinopathy caused by a glutamic acid to lysine substitution in beta-globin, leading to mild hemolytic anemia and splenomegaly.Sickle Cell AnemiaSickle Cell Anemia is a genetic disorder causing abnormal hemoglobin that leads to sickle-shaped red blood cells, resulting in anemia, pain, and organ damage.