Intrauterine Adhesions

Overview


Plain-Language Overview

Intrauterine adhesions are bands of scar tissue that form inside the uterus, often after injury or infection. This condition affects the female reproductive system and can interfere with normal menstrual flow and fertility. The scar tissue can cause the walls of the uterus to stick together, leading to symptoms like reduced or absent menstrual periods and difficulty becoming pregnant. It may also cause painful menstruation or recurrent pregnancy loss. Diagnosis and treatment are important to restore normal uterine function and improve reproductive outcomes.

Clinical Definition

Intrauterine adhesions (also known as Asherman syndrome) are characterized by the formation of fibrous scar tissue within the endometrial cavity, resulting from trauma to the basal layer of the endometrium. The most common cause is traumatic uterine procedures such as dilation and curettage, especially after pregnancy-related events like miscarriage or postpartum hemorrhage. This scarring leads to partial or complete obliteration of the uterine cavity, causing amenorrhea, hypomenorrhea, infertility, or recurrent pregnancy loss. The condition disrupts normal endometrial regeneration and impairs implantation. Diagnosis is clinically significant due to its impact on reproductive health and potential for treatment to restore uterine anatomy.

Clinical Presentation


Diagnostic Workup


Pathophysiology


Treatments


Prevention


Outcome & Complications


Differential Diagnoses


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