Pulmonary Emboli (Fat)
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Overview
Plain-Language Overview
Pulmonary emboli (fat) occur when fat droplets enter the blood vessels of the lungs, blocking blood flow. This condition mainly affects the respiratory system and can cause difficulty breathing, chest pain, and low oxygen levels. Fat emboli often happen after bone fractures or trauma that releases fat from the bone marrow into the bloodstream. The blockage can prevent oxygen from reaching the body’s tissues, leading to serious complications. Symptoms may also include confusion or a rash due to fat particles affecting other organs. This condition requires prompt medical attention because it can impair lung function and overall health.
Clinical Definition
Pulmonary emboli (fat) is a form of embolism characterized by the occlusion of the pulmonary vasculature by fat globules, typically released from disrupted bone marrow following long bone fractures or severe trauma. The fat droplets enter the venous circulation, travel to the lungs, and cause mechanical obstruction and an inflammatory response in the pulmonary capillaries. This leads to hypoxemia, respiratory distress, and potentially acute respiratory failure. The syndrome is part of the broader fat embolism syndrome (FES), which also includes systemic manifestations such as petechial rash and neurological symptoms. The pathophysiology involves both physical obstruction and biochemical injury from free fatty acids. Recognition of this condition is critical due to its potential for rapid deterioration and high morbidity.