Gender dysphoria (General)
Overview
Plain-Language Overview
Gender dysphoria is a condition where a person feels a strong and persistent discomfort with the sex they were assigned at birth. It primarily involves the psychological and emotional aspects of identity related to gender. This condition affects the brain and mental health, leading to distress that can impact daily functioning and well-being. People with gender dysphoria often experience a mismatch between their internal sense of gender and their physical body. This can cause significant anxiety, depression, and social difficulties. Understanding and recognizing these feelings is important for proper support and care.
Clinical Definition
Gender dysphoria is defined as a marked incongruence between an individual's experienced or expressed gender and the gender assigned at birth, causing clinically significant distress or impairment. The core pathology involves a persistent identification with a gender different from the natal sex, often accompanied by a strong desire to be treated as the experienced gender. The exact cause is multifactorial, involving complex interactions of biological, psychological, and social factors. It is distinct from gender nonconformity without distress. The condition is clinically significant due to its impact on mental health, social functioning, and quality of life. Diagnosis requires careful assessment to differentiate from other psychiatric or developmental disorders.
Inciting Event
Locked content
Latency Period
Locked content
Diagnostic Delay
Locked content
Clinical Presentation
Signs & Symptoms
Locked content
History of Present Illness
Locked content
Past Medical History
Locked content
Family History
Locked content
Physical Exam Findings
Locked content
Diagnostic Workup
Diagnostic Criteria
Locked content
Pathophysiology
Key Mechanisms
Locked content
Organs
Locked content
Tissues
Locked content
Cells
Locked content
Chemical Mediators
Locked content
Treatments
Pharmacological Treatments
Locked content
Non-pharmacological Treatments
Locked content
Prevention
Pharmacological Prevention
Locked content
Non-pharmacological Prevention
Locked content
Outcome & Complications
Complications
Locked content
Short-term Sequelae
Locked content
Long-term Sequelae
Locked content
Differential Diagnoses
Differentials
Locked content