Deep partial-thickness burn (Epidermis and reticular dermis)

Overview


Plain-Language Overview

A deep partial-thickness burn affects both the outer skin layer (epidermis) and the deeper reticular dermis, which is part of the skin's second layer. This type of burn damages important structures like hair follicles and sweat glands, which can affect the skin's ability to heal and regulate temperature. The injury causes intense pain, redness, and blistering, and the skin may appear wet or mottled. Because the damage extends deeper than superficial burns, healing takes longer and may result in scarring or changes in skin texture. This condition primarily involves the integumentary system, which protects the body from infection and helps control body temperature.

Clinical Definition

Deep partial-thickness burns involve destruction of the epidermis and extend into the reticular dermis, sparing some dermal appendages but causing significant tissue injury. These burns typically result from exposure to thermal, chemical, or electrical sources and are characterized by severe pain, blistering, and a mottled, wet appearance due to plasma leakage. The injury disrupts the skin's barrier function, increasing the risk of infection and fluid loss. Healing occurs through re-epithelialization from surviving dermal structures but is slower than superficial burns and often leads to hypertrophic scarring or contractures. Accurate assessment of burn depth is critical for management and prognosis.

Inciting Event

Locked content

Latency Period

Locked content

Diagnostic Delay

Locked content

Clinical Presentation


Signs & Symptoms

Locked content

History of Present Illness

Locked content

Past Medical History

Locked content

Family History

Locked content

Physical Exam Findings

Locked content

Diagnostic Workup


Diagnostic Criteria

Locked content

Pathophysiology


Key Mechanisms

Locked content

Organs

Locked content

Tissues

Locked content

Cells

Locked content

Chemical Mediators

Locked content

Treatments


Pharmacological Treatments

Locked content

Non-pharmacological Treatments

Locked content

Prevention


Pharmacological Prevention

Locked content

Non-pharmacological Prevention

Locked content

Outcome & Complications


Complications

Locked content

Short-term Sequelae

Locked content

Long-term Sequelae

Locked content

Differential Diagnoses


Differentials

Locked content

Medical Disclaimer: The content on this site is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. If you think you may be experiencing a medical emergency, call 911 or your local emergency number immediately. Always consult a licensed healthcare professional with questions about a medical condition.

Artificial Intelligence Use: Portions of this site’s content were generated or assisted by AI and reviewed by Erik Romano, MD; however, errors or omissions may occur.

USMLE® is a registered trademark of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). Doctogenic and Roscoe & Romano are not affiliated with, sponsored by, or endorsed by the USMLE, FSMB, or NBME. Neither FSMB nor NBME has reviewed or approved this content. "USMLE Step 1" and "USMLE Step 2 CK" are used only to identify the relevant examinations.