Rosacea
Overview
Plain-Language Overview
Rosacea is a common skin condition that mainly affects the face, causing redness, visible blood vessels, and sometimes small, red, pus-filled bumps. It primarily involves the skin's blood vessels and immune system, leading to persistent facial flushing and irritation. The condition often appears on the cheeks, nose, forehead, and chin. People with rosacea may experience episodes of worsening symptoms triggered by factors like sun exposure, hot drinks, or stress. Although it is not contagious or life-threatening, rosacea can significantly impact a person's appearance and self-confidence.
Clinical Definition
Rosacea is a chronic inflammatory skin disorder characterized by persistent facial erythema, telangiectasias, papules, and pustules primarily affecting the central face. The pathogenesis involves dysregulation of the innate immune system, abnormal vascular reactivity, and possibly colonization by Demodex mites. It is classified into subtypes including erythematotelangiectatic, papulopustular, phymatous, and ocular rosacea. The condition is more common in fair-skinned adults aged 30-50 and has a relapsing-remitting course. Major clinical significance lies in its potential to cause disfiguring skin changes and ocular complications if untreated. Diagnosis is clinical, based on characteristic features and exclusion of mimics such as acne vulgaris or seborrheic dermatitis.
Inciting Event
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Latency Period
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Diagnostic Delay
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Clinical Presentation
Signs & Symptoms
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History of Present Illness
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Past Medical History
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Family History
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Physical Exam Findings
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Diagnostic Workup
Diagnostic Criteria
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Pathophysiology
Key Mechanisms
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Organs
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Tissues
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Cells
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Chemical Mediators
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Treatments
Pharmacological Treatments
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Non-pharmacological Treatments
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Prevention
Pharmacological Prevention
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Non-pharmacological Prevention
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Outcome & Complications
Complications
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Short-term Sequelae
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Long-term Sequelae
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Differential Diagnoses
Differentials
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