Acute Pancreatitis
Overview
Plain-Language Overview
Acute pancreatitis is a sudden inflammation of the pancreas, an organ that helps with digestion and blood sugar regulation. This condition causes the pancreas to become swollen and painful, often leading to severe abdominal pain. It can affect how the body processes food and can cause symptoms like nausea, vomiting, and fever. The inflammation can sometimes spread to other parts of the body, causing more serious health problems. Early recognition and treatment are important to manage symptoms and prevent complications.
Clinical Definition
Acute pancreatitis is an inflammatory condition characterized by sudden onset of pancreatic inflammation due to premature activation of pancreatic enzymes, leading to autodigestion of pancreatic tissue. The most common causes include gallstones obstructing the pancreatic duct and chronic alcohol use causing direct pancreatic injury. This results in acute abdominal pain, systemic inflammatory response, and potential local complications such as pancreatic necrosis or pseudocyst formation. The disease can range from mild, self-limited inflammation to severe, life-threatening illness with multi-organ failure. Diagnosis and management focus on identifying the underlying cause and preventing complications.
Inciting Event
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Latency Period
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Diagnostic Delay
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Clinical Presentation
Signs & Symptoms
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History of Present Illness
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Past Medical History
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Family History
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Physical Exam Findings
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Diagnostic Workup
Diagnostic Criteria
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Pathophysiology
Key Mechanisms
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Organs
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Tissues
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Cells
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Treatments
Pharmacological Treatments
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Non-pharmacological Treatments
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Prevention
Pharmacological Prevention
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Non-pharmacological Prevention
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Outcome & Complications
Complications
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Long-term Sequelae
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Differential Diagnoses
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