Annular Pancreas

Overview


Plain-Language Overview

Annular Pancreas is a rare birth defect affecting the digestive system, where a ring of pancreatic tissue surrounds the first part of the small intestine called the duodenum. This abnormal ring can cause a blockage, making it difficult for food to pass from the stomach into the intestines. Symptoms often appear in newborns or infants and include vomiting, feeding difficulties, and abdominal swelling. In some cases, it may not cause symptoms until later in life. The condition involves the pancreas, an organ important for digestion and blood sugar regulation. Diagnosis usually requires imaging tests to see the abnormal pancreatic tissue. Treatment often involves surgery to relieve the obstruction.

Clinical Definition

Annular Pancreas is a congenital anomaly characterized by a ring of pancreatic tissue encircling the descending portion of the duodenum, resulting from abnormal migration of the ventral pancreatic bud during embryogenesis. This aberrant pancreatic ring can cause duodenal obstruction, leading to symptoms such as bilious vomiting and feeding intolerance, especially in neonates. The condition is significant due to its potential to cause partial or complete duodenal obstruction and associated complications like pancreatitis or peptic ulcer disease. It is often associated with other congenital anomalies such as Down syndrome and duodenal atresia. The diagnosis is important for differentiating from other causes of neonatal intestinal obstruction. Surgical intervention is typically required to bypass or relieve the obstruction.

Inciting Event

Locked content

Latency Period

Locked content

Diagnostic Delay

Locked content

Clinical Presentation


Signs & Symptoms

Locked content

History of Present Illness

Locked content

Past Medical History

Locked content

Family History

Locked content

Physical Exam Findings

Locked content

Diagnostic Workup


Diagnostic Criteria

Locked content

Pathophysiology


Key Mechanisms

Locked content

Organs

Locked content

Tissues

Locked content

Cells

Locked content

Chemical Mediators

Locked content

Treatments


Pharmacological Treatments

Locked content

Non-pharmacological Treatments

Locked content

Prevention


Pharmacological Prevention

Locked content

Non-pharmacological Prevention

Locked content

Outcome & Complications


Complications

Locked content

Short-term Sequelae

Locked content

Long-term Sequelae

Locked content

Differential Diagnoses


Differentials

Locked content

Medical Disclaimer: The content on this site is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. If you think you may be experiencing a medical emergency, call 911 or your local emergency number immediately. Always consult a licensed healthcare professional with questions about a medical condition.

Artificial Intelligence Use: Portions of this site’s content were generated or assisted by AI and reviewed by Erik Romano, MD; however, errors or omissions may occur.

USMLE® is a registered trademark of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). Doctogenic and Roscoe & Romano are not affiliated with, sponsored by, or endorsed by the USMLE, FSMB, or NBME. Neither FSMB nor NBME has reviewed or approved this content. "USMLE Step 1" and "USMLE Step 2 CK" are used only to identify the relevant examinations.