Focal Nodular Hyperplasia (Liver)

Focal Nodular Hyperplasia (FNH) is a benign liver condition characterized by a small, localized growth in the liver tissue. It involves the liver, an essential organ responsible for filtering blood, producing bile, and metabolizing nutrients. This growth is usually noncancerous and does not typically cause symptoms or harm liver function. Most people with FNH do not experience pain or noticeable health problems, and it is often found incidentally during imaging tests for other reasons. The main concern is distinguishing it from other liver lesions that may require different management. FNH is associated with a central scar and abnormal blood vessels within the lesion. It generally does not affect overall health or liver performance.

Focal Nodular Hyperplasia (FNH) is a benign hepatic lesion characterized by a localized hyperplastic response of hepatocytes to a vascular malformation. It is thought to arise from a hyperplastic reaction to an anomalous artery causing increased blood flow, leading to nodular growth. The lesion typically contains a central stellate scar with fibrous septa and malformed vessels. FNH is most common in young to middle-aged adults, especially women, and is usually asymptomatic. It is important clinically because it must be differentiated from malignant liver tumors and other benign lesions such as hepatic adenomas. Histologically, FNH shows normal hepatocytes arranged in nodules separated by fibrous septa containing abnormal vessels and bile duct proliferation. The lesion does not have malignant potential and rarely requires intervention.