Squamous Cell Carcinoma (Penis)

Penile cancer is a rare type of cancer that affects the skin and tissues of the penis, primarily involving the squamous cells which are flat cells covering the surface. This condition can cause symptoms such as a growth or sore on the penis, which may be painful or bleed. It mainly affects the male reproductive system and can impact urinary and sexual function if it spreads. Early detection is important because the cancer can grow locally and spread to nearby lymph nodes. Risk factors include poor hygiene, smoking, and infection with human papillomavirus (HPV). Treatment often involves surgery, radiation, or chemotherapy depending on the stage.

Squamous Cell Carcinoma (Penis) is a malignant neoplasm arising from the squamous epithelium of the penile skin or mucosa. It is primarily caused by chronic inflammation, HPV infection (especially types 16 and 18), and other risk factors such as phimosis and smoking. The tumor typically presents as an ulcerative or exophytic lesion on the glans, foreskin, or shaft. Histologically, it shows keratinizing squamous cells with varying degrees of differentiation. This carcinoma is clinically significant due to its potential for local invasion and regional lymph node metastasis, which strongly influence prognosis. Early diagnosis and staging are critical for effective management and improved survival.